| Date | Location | Result | |
| 03/18/16 | Spokane Arena, Spokane, Wash. | Oregon 91, Holy Cross 52 | Box score |
| 03/16/16 | University of Dayton Arena, Dayton, Ohio | Holy Cross 59, Southern 55 | Box score |
| 03/09/16 | Stabler Arena, Bethlehem, Pa. | Holy Cross 59, Lehigh 56 | Box score |
| 03/06/16 | Christl Arena, West Point, N.Y. | Holy Cross 60, Army West Point 38 | Box score |
| 03/03/16 | Sojka Pavilion, Lewisburg, Pa. | Holy Cross 77, Bucknell 72 (2OT) | Box score |
| 03/01/16 | Reitz Arena, Baltimore, Md. | Holy Cross 72, Loyola (Md.) 67 | Box score |
| 02/27/16 | Case Gymnasium, Boston, Mass. | Boston University 83, Holy Cross 68 | Box score |
| 02/24/16 | Reitz Arena, Baltimore, Md. | Loyola (Md.) 78, Holy Cross 63 | Box score |
| 02/21/16 | Hart Center, Worcester, Mass. | American 71, Holy Cross 70 (OT) | Box score |
| 02/17/16 | Christl Arena, West Point, N.Y. | Army West Point 72, Holy Cross 68 | Box score |
| 02/15/16 | Stabler Arena, Bethlehem, Pa. | Lehigh 64, Holy Cross 59 | Box score |
| 02/10/16 | Hart Center, Worcester, Mass. | Holy Cross 67, Lafayette 53 | Box score |
| 02/06/16 | Hart Center, Worcester, Mass. | Bucknell 77, Holy Cross 52 | Box score |
| 02/01/16 | Bender Arena, Washington, D.C. | American 58, Holy Cross 45 | Box score |
| 01/30/16 | Hart Center, Worcester, Mass. | Holy Cross 87, Navy 80 (OT) | Box score |
| 01/27/16 | Hart Center, Worcester, Mass. | Loyola (Md.) 71, Holy Cross 54 | Box score |
| 01/24/16 | Cotterell Court, Hamilton, N.Y. | Colgate 76, Holy Cross 61 | Box score |
| 01/20/16 | Hart Center, Worcester, Mass. | Holy Cross 69, Army West Point 65 | Box score |
| 01/16/16 | Hart Center, Worcester, Mass. | Lehigh 87, Holy Cross 66 | Box score |
| 01/13/16 | Kirby Sports Center, Easton, Pa. | Lafayette 65, Holy Cross 52 | Box score |
| 01/09/16 | Sojka Pavilion, Lewisburg, Pa. | Bucknell 98, Holy Cross 71 | Box score |
| 01/06/16 | Hart Center, Worcester, Mass. | Holy Cross 65, Colgate 63 | Box score |
| 01/02/16 | Alumni Hall, Annapolis, Md. | Navy 65, Holy Cross 60 | Box score |
| 12/30/15 | Hart Center, Worcester, Mass. | Holy Cross 80, Boston University 64 | Box score |
| 12/21/15 | Hart Center, Worcester, Mass. | Holy Cross 76, Maine 75 | Box score |
| 12/12/15 | Chase Family Arena, West Hartford, Conn. | Holy Cross 90, Hartford 68 | Box score |
| 12/09/15 | Allen Fieldhouse, Lawrence, Kan. | Kansas 92, Holy Cross 59 | Box score |
| 12/05/15 | Hart Center, Worcester, Mass. | Albany 88, Holy Cross 84 (OT) | Box score |
| 12/02/15 | Thomas M. Ryan Center, Kingston, R.I. | Rhode Island 74, Holy Cross 56 | Box score |
| 11/29/15 | Hart Center, Worcester, Mass. | Holy Cross 50, Harvard 49 | Box score |
| 11/25/15 | Hart Center, Worcester, Mass. | Holy Cross 69, Sacred Heart 60 | Box score |
| 11/22/15 | TD Bank Sports Center, Hamden, Conn. | Quinnipiac 62, Holy Cross 56 | Box score |
| 11/19/15 | Hart Center, Worcester, Mass. | New Hampshire 73, Holy Cross 69 | Box score |
| 11/16/15 | Pizzitola Sports Center, Providence, RI | Brown 71, Holy Cross 55 | Box score |
| 11/13/15 | McCann Arena, Poughkeepsie, N.Y. | Holy Cross 67, Marist 64 | Box score |